Optical biosensors based on the evanescent field of surface plasmons 1, 2, 3, 4, optical waveguide interferometers 2, 3, photonic crystals 2 or resonant waveguide gratings (RWG) 3, 5 are widely utilized to directly analyze biochemical and cellular interactions without the need of any biomolecular labels. These numerical findings are supported with experimental results, where the cut-off sensing mode was identified. Consequently, it is sufficient to monitor the intensity change of the near cut-off sensing mode, which leads to a simpler sensor design compared to those setups where the resonant wavelength shift of the guided mode is monitored with high precision. The operating wavelength and the sensitivity of the proposed device can be tuned by varying the geometrical parameters of the corrugated waveguide. These results may lead to the development of highly sensitive integrated sensors, which have a simple design and therefore are cost-effective for a wide range of applications. The numerical simulations reveal the high sensitivity of the guided mode intensity near the cut-off wavelength for any refractive index change along the waveguide. Near cut-off and far from cut-off modes are investigated, and their characteristics and suitability for sensing are compared. Numerical simulations and analytical calculations are performed to support the design of grating-coupled planar optical waveguides for biological sensing.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |